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Nietlispach Group

NMR spectroscopy of membrane proteins

Studying at Cambridge

The Nietlispach Group

Recent Papers

Insight into partial agonism by observing multiple equilibria for ligand-bound and Gs-mimetic nanobody-bound β1-adrenergic receptor.
Andras S. Solt, Mark J. Bostock, Binesh Shrestha, Prashant Kumar, Tony Warne, Christopher G. Tate & Daniel Nietlispach, Nature Communications (2017) 8, 1795
(doi: 10.1038/s41467-017-02008-y)

An adaptable phospholipid membrane mimetic system for solution NMR studies of membrane proteins.
Chih-Ta Henry Chien, Lukas R. Helfinger, Mark J. Bostock, Andras Solt, Yi Lei Tan, and Daniel Nietlispach, Journal of the American Chemical Society (2017) 139, 14829-14832
(doi: 10.1021/jacs.7b06730)

Preparation of saposin nanodiscs for NMR

Compressed Sensing ℓ1-Norm Minimisation in Multidimensional NMR Spectroscopy
Mark J. Bostock, Daniel J. Holland and Daniel Nietlispach, from Fast NMR Data Acquisition - Beyond the Fourier Transform (RSC publishing) (2017)
(doi:10.1039/9781782628361-00267)

Improving resolution in multidimensional NMR using random quadrature detection with compressed sensing reconstruction.
Mark J. Bostock, Daniel J. Holland, Daniel Nietlispach, Journal of Biomolecular NMR (2017) 68, 67-77
(doi:10.1007/s10858-016-0062-9)